Think about the hurt caused by their behaviours and the impact it made to your relationship.
Depending on the issue you can decide whether you're going derictly or indirectly.
If you're going direct, think about what you're going to say. Something thoughtful and right.
If your going indirect, think about the right actio to take in order to hint them.
Take the real action. Be confidence and mean everything you do. Anything you do is right and never apologize.
If the indirect/far away fails, either leave them or approach them bluntly. If things don't seem to get right, this might be the end of the friendship. Gladly walk away.